产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

MMP9 polyclonal antibody

货号: BS6893

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6893

Product Name :MMP9 polyclonal antibody

Swiss-Prot :P14780

Host :Rabbit

Reactivity :Human,Mouse

Applications :IHC

Application_all :IHC: 1:50~1:200

Background :The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or taphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92-kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is down-regulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MMP9 polyclonal antibody detects endogenous levels of MMP9 protein.

BiowMW :~ 67 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Tumor Angiogenesis,Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB; MMP9; CLG4B

Immunogen :Recombinant full length Human MMP9.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry of paraffin-embedded mouse heart using MMP9 antibody at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded human liver damage using MMP9 antibody at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded mouse liver using MMP9 antibody at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded mouse kidney using MMP9 antibody at dilution of 1:100 (40x lens).

Silencing of plasminogen activator inhibitor-1 suppresses colorectal cancer progression and liver metastasis

JournalSurgery

ApplicationWB

IF3.982

SpeciesHuman

PMID26275833
Korean Byungkyul - Citrus platymamma Hort.et Tanaka flavonoids induces cell cycle arrest and apoptosis, regulating MMP protein expression in Hep3B hepatocellular carcinoma cells

JournalInternational Journal Of Oncology

ApplicationWB

IF3.899

SpeciesHuman

PMID28035361
Downregulation of FoxM1 inhibits proliferation, invasion and angiogenesis of HeLa cells in vitro and in vivo

JournalInternational Journal Of Oncology

ApplicationWB

IF3.571

SpeciesHuman,Mouse

PMID25201015
Fangchinoline as a kinase inhibitor targets FAK and suppresses FAK-mediated signaling pathway in A549

JournalJournal Of Drug Targeting

ApplicationWB

IF3.277

SpeciesHuman

PMID25539072
Reno-protection of G004, a novel anti-diabetic sulfonylurea in db/db mice

JournalNaunyn-Schmiedebergs Archives Of Pharmacology

ApplicationWB,IHC

IF3

SpeciesMouse

PMID