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VDAC1 polyclonal antibody

货号: BS6760

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6760

Product Name :VDAC1 polyclonal antibody

Swiss-Prot :P21796

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background :Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :VDAC1 polyclonal antibody detects endogenous levels of VDAC1 protein.

BiowMW :~ 32 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Warburg Effect,

Alternative Name :Voltage-dependent anion-selective channel protein 1; VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; VDAC1; VDAC

Immunogen :Recombinant full length Human VDAC1.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of VDAC1 polyclonal antibody

Immunohistochemistry (IHC) analysis of VDAC1 polyclonal antibody in paraffin-embedded Human Stomach Cancer tissue.

Immunofluorescence analysis of Hela cells, using VDAC1 polyclonal antibody

Oridonin Attenuates Aβ1–42-Induced Neuroinflammation and Inhibits NF-κB Pathway

JournalPLoS One

ApplicationWB

IF2.74

SpeciesMouse

PMID
Malibatol A protects against brain injury through reversing mitochondrial dysfunction in experimental stroke

JournalNeurochemistry International

ApplicationWB

IF3.881

SpeciesMouse

PMID25447763
Orientin alleviates cognitive deficits and oxidative stress in Aβ1–42-induced mouse model of Alzheimer's disease

JournalLife Sciences

ApplicationWB

IF3.647

SpeciesMouse

PMID25497709
Oridonin Attenuates Synaptic Loss and Cognitive Deficits in an Aβ1–42-Induced Mouse Model of Alzheimer’s Disease

JournalPLoS One

ApplicationWB

IF2.74

SpeciesMouse

PMID26974541
Valproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy

JournalNeuroscience Letters

ApplicationWB

IF2.274

SpeciesHuman

PMID27956235