产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

VDAC1 polyclonal antibody

货号: BS6760

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6760

Product Name :VDAC1 polyclonal antibody

Swiss-Prot :P21796

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background :Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :VDAC1 polyclonal antibody detects endogenous levels of VDAC1 protein.

BiowMW :~ 32 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Warburg Effect,

Alternative Name :Voltage-dependent anion-selective channel protein 1; VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; VDAC1; VDAC

Immunogen :Recombinant full length Human VDAC1.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of VDAC1 polyclonal antibody

Immunohistochemistry (IHC) analysis of VDAC1 polyclonal antibody in paraffin-embedded Human Stomach Cancer tissue.

Immunofluorescence analysis of Hela cells, using VDAC1 polyclonal antibody

Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages

JournalImmunity

ApplicationWB

IF21.522

SpeciesHuman,Mouse

PMID30366764
Benzo(a)pyren-7,8-dihydrodiol-9,10-epoxide induces human trophoblast Swan 71 cell dysfunctions due to cell apoptosis through disorder of mitochondrial fission/fusion

JournalEnvironmental Pollution

ApplicationWB

IF8.071

SpeciesHuman

PMID29144987