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RAD50 monoclonal antibody

货号: MB22122

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB22122

Product Name :RAD50 monoclonal antibody

Swiss-Prot :Q92878

Host :Mouse

Reactivity :Human,Rat

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2a

BiowMW :154kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NBSLD; RAD502; hRad50

Immunogen :Purified recombinant fragment of human RAD50 (AA: 228-359) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using RAD50 mouse mAb against C6 (1) and HepG2 (2) cell lysate.

Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using RAD50 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）