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ZBTB7B monoclonal antibody

货号: MB21303

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21303

Product Name :ZBTB7B monoclonal antibody

Swiss-Prot :O15156

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000

Background :ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :58kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :THPOK; ZFP67; ZBTB15; c-Krox; hcKrox; ZNF857B; DKFZp686G01254; ZBTB7B

Immunogen :Purified recombinant fragment of human ZBTB7B expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ZBTB7B mAb against HEK293 (1,2) cell lysate.

Immunohistochemical analysis of paraffin-embedded human Breast tissues using anti-ZBTB7B mouse mAb

Immunofluorescence analysis of Hela cells using ZBTB7B mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin

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