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Desmin monoclonal antibody

货号: MB21084

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21084

Product Name :Desmin monoclonal antibody

Swiss-Prot :P17661

Host :Mouse

Reactivity :Human,Mouse,Rat,Rabbit,Monkey

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :54kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Desmin

Immunogen :Purified recombinant fragment of Desmin expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using Desmin mouse mAb against PC-12(1)NIH/3T3(2 )NRK(3)C2C12(4)C6(5) cell lysate.

Immunohistochemical analysis of paraffin-embedded human smooth musde sarcoma, showing cytoplasmic localization using Desmin mouse mAb with DAB staining.