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MyD88 (V220) polyclonal antibody

货号: BS3521

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS3521

Product Name :MyD88 (V220) polyclonal antibody

Swiss-Prot :Q99836

Host :Rabbit

Reactivity :Human, Mouse, Rat, Bovine, Monkey, Pig, Sheep

Applications :WB, IF/ICC,IHC

Application_all :WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200|IHC,1:100 - 1:500

Background :The myeloid differentiation protein MyD88 was originally characterized as a protein upregulated in myeloleukemic cells following IL-6-induced growth arrest and terminal differentiation. MyD88 is now known to function as an adaptor protein for the association of IRAK with the IL-1 receptor. MyD88 is functionally homologous to the adaptor protein tube in the Toll signaling pathway of Drosophilia, and both proteins are members of the Toll/IL-1R superfamily. MyD88 contains a characteristic N-terminal death domain that is essential for NFκB activation and an adjacent Toll/IL-1R homology domain (TIR domain). Collectively, these domains enable the protein-protein interactions of MyD88 with IRAK and the IL-1 receptor complex.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MyD88 (V220) polyclonal antibody detects endogenous levels of MyD88 protein.

BiowMW :~ 33, 31, 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Toll-like Receptor signaling,

Alternative Name :Myeloid differentiation primary response protein MyD88

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MYD88.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of MYD88 expression in HEK293T (A), Hela (B), mouse lung (C), mouse muscle (D), mouse spleen (E), rat muscle (F), rat spleen (G) whole cell lysates.

Immunohistochemical analysis of MYD88 staining in human brain formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of MYD88 staining in Jurkat cells.

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