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Estrogen Receptor alpha monoclonal antibody

货号: MB10892

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB10892

Product Name :Estrogen Receptor alpha monoclonal antibody

Swiss-Prot :P03372

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-F,IHC-P,ICC/IF,IP,ChIP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 ChIP: 1/20

Background :ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 66 kDa; Observed MW: 66 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha

Immunogen :A synthetic peptide of human Estrogen Receptor alpha

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Estrogen Receptor alpha in K562, Hela lysates using Estrogen Receptor alpha antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Estrogen Receptor alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.