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CD63 polyclonal antibody

货号: BS72936

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS72936

Product Name :CD63 polyclonal antibody

Swiss-Prot :P08962

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IHC

Application_all :WB 1:500 - 1:1000 IHC 1:50 - 1:200

Background :The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD63 polyclonal antibody detects endogenous levels of CD63 protein.

BiowMW :~ 53 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Tumor-Infiltrating Immune Cell Marker Guide,Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :LAMP-3; ME491; MLA1; OMA81H; TSPAN30

Immunogen :Synthetic peptide, corresponding to Human CD63.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD63 polyclonal antibody at 1:500 dilution LaneA:The Liver tissue lysate of Rat(40ug)

Immunohistochemistry of paraffin-embedded human lung cancer using CD63 antibody.

Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro

JournalStem Cell Research & Therapy

ApplicationWB

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SpeciesRat

PMID23618405
Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

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HucMSC exosome-transported 14-3-3ζ prevents the injury of cisplatin to HK-2 cells by inducing autophagy in vitro

JournalCytotherapy

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IF4.218

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PMID28943243
Downregulated Serum Exosomal miR-451a Expression Correlates With Renal Damage and Its Intercellular Communication Role in Systemic Lupus Erythematosus

JournalFrontiers in Immunology

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IF7.561

SpeciesHuman

PMID33643314
Biomimetic silibinin-loaded macrophage-derived exosomes induce dual inhibition of Aβ aggregation and astrocyte activation to alleviate cognitive impairment in a model of Alzheimer's disease

JournalMaterials Science & Engineering C-Materials for Biological Applications

ApplicationWB

IF7.328

SpeciesMouse

PMID34579884