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CD63 polyclonal antibody

货号: BS72936

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS72936

Product Name :CD63 polyclonal antibody

Swiss-Prot :P08962

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IHC

Application_all :WB 1:500 - 1:1000 IHC 1:50 - 1:200

Background :The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD63 polyclonal antibody detects endogenous levels of CD63 protein.

BiowMW :~ 53 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Tumor-Infiltrating Immune Cell Marker Guide,Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :LAMP-3; ME491; MLA1; OMA81H; TSPAN30

Immunogen :Synthetic peptide, corresponding to Human CD63.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD63 polyclonal antibody at 1:500 dilution LaneA:The Liver tissue lysate of Rat(40ug)

Immunohistochemistry of paraffin-embedded human lung cancer using CD63 antibody.

Hypoxic glioblastoma release exosomal VEGF-A induce the permeability of blood-brain barrier

JournalBiochemical And Biophysical Research Communications

ApplicationWB

IF2.705

SpeciesHuman

PMID29787762
Gastric cancer cell-originated small extracellular vesicle induces metabolic reprogramming of BM-MSCs through ERK-PPARγ-CPT1A signaling to potentiate lymphatic metastasis

JournalCancer Cell International

ApplicationWB

IF6.429

SpeciesHuman

PMID37158903
Exosomal miR-486 derived from bone marrow mesenchymal stem cells promotes angiogenesis following cerebral ischemic injury by regulating the PTEN/Akt pathway

JournalScientific Reports

ApplicationWB

IF3.8

SpeciesRat

PMID39103424
De-Differentiation of Corneal Epithelial Cells Into Functional Limbal Epithelial Stem Cells After the Ablation of Innate Stem Cells

Journal10.1167/iovs.65.13.32

ApplicationIF

IF5

SpeciesRat,Mouse

PMID39546294