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PPARγ polyclonal antibody

货号: BS6442

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6442

Product Name :PPARγ polyclonal antibody

Swiss-Prot :P37231

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :IHC,IF/ICC

Application_all :IHC,1:50 - 1:200|IF/ICC,1:50 - 1:20

Background :This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :57KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CIMT1;GLM1;NR1C3;PPARG1;PPARG2;PPARgamma;PPAR gamma;PPARG

Immunogen :Recombinant fusion protein of human PPARγ(NP_056953.2).

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry of paraffin-embedded mouse heart using PPARγ Rabbit pAb at dilution of 1:200 .Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunohistochemistry of paraffin-embedded mouse liver using PPARγ Rabbit pAb at dilution of 1:200 .Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunofluorescence analysis of U2OS cells using PPARγ Rabbit pAb at dilution of 1:200 . Blue: DAPI for nuclear staining.

Asiatic Acid Isolated From Centella Asiatica Inhibits TGF-β1-induced Collagen Expression in Human Keloid Fibroblasts via PPAR-γ Activation

JournalInternational Journal of Biological Sciences

ApplicationWB

IF4.858

SpeciesHuman

PMID24250248
Mark4 promotes adipogenesis and triggers apoptosis in 3T3-L1 adipocytes by activating JNK1 and inhibiting p38MAPK pathways

JournalBiology Of The Cell

ApplicationWB

IF4.458

SpeciesMouse

PMID
MicroRNA-130b and microRNA-374b mediate the effect of maternal dietary protein on offspring lipid metabolism in Meishan pigs

JournalBritish Journal Of Nutrition

ApplicationWB

IF3.718

SpeciesPig

PMID22958366
Double antioxidant activities of rosiglitazone against high glucose-induced oxidative stress in hepatocyte

JournalToxicology In Vitro

ApplicationWB

IF3.5

SpeciesHuman

PMID
Mitochondrial Dysfunction Mediates Aldosterone-Induced Podocyte Damage: A Therapeutic Target of PPARγ

JournalAmerican Journal Of Pathology

ApplicationWB

IF3.491

SpeciesMouse

PMID