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PPARγ polyclonal antibody

货号: BS6442

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6442

Product Name :PPARγ polyclonal antibody

Swiss-Prot :P37231

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :IHC,IF/ICC

Application_all :IHC,1:50 - 1:200|IF/ICC,1:50 - 1:20

Background :This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :57KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CIMT1;GLM1;NR1C3;PPARG1;PPARG2;PPARgamma;PPAR gamma;PPARG

Immunogen :Recombinant fusion protein of human PPARγ(NP_056953.2).

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry of paraffin-embedded mouse heart using PPARγ Rabbit pAb at dilution of 1:200 .Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunohistochemistry of paraffin-embedded mouse liver using PPARγ Rabbit pAb at dilution of 1:200 .Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunofluorescence analysis of U2OS cells using PPARγ Rabbit pAb at dilution of 1:200 . Blue: DAPI for nuclear staining.

The endocrine disruptor diethylstilbestrol induces adipocyte differentiation and promotes obesity in mice

JournalToxicology And Applied Pharmacology

ApplicationWB

IF3.347

SpeciesMouse

PMID
Influence of Rosiglitazone on the Expression of PPARγ, NF-κB, and TNF-α in Rat Model of Ulcerative Colitis

JournalGastroenterology Research and Practice

ApplicationIHC

IF2.26

SpeciesRat

PMID
Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner

JournalJournal of Neuroinflammation

ApplicationWB

IF5.793

SpeciesMouse

PMID25889216
Erythropoietin alleviates hepatic insulin resistance via PPARγ-dependent AKT activation

JournalScientific Reports

ApplicationWB

IF4.011

SpeciesMouse,Human

PMID26643367
Effects of Caloric Intake on Learning and Memory Function in Juvenile C57BL/6J Mice

JournalBiomed Research International

ApplicationWB

IF2.276

SpeciesMouse

PMID26491687