产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

BAMBI polyclonal antibody

货号: BS6435

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6435

Product Name :BAMBI polyclonal antibody

Swiss-Prot :Q13145

Host :Rabbit

Reactivity :Human,Rat

Applications :WB IF

Application_all :WB: 1:500~1:2000 IF: 1:50~1:200

Background :BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA), also designated Non-metastatic gene A protein, is a membrane spanning glycoprotein that acts as a negative regulator of TGF-β signaling during development. The BAMBI family of proteins are related to type I TGF-β receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of β-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :BAMBI polyclonal antibody detects endogenous levels of BAMBI protein.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BMP and activin membrane-bound inhibitor homolog; Non-metastatic gene A protein; Putative transmembrane protein NMA; BAMBI; NMA

Immunogen :Recombinant full length Human BAMBI.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cells, using BAMBI antibody.

Immunofluorescence analysis of HeLa cell using BAMBI antibody. Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）