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ATP6AP1 polyclonal antibody

货号: BS6251

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS6251

Product Name :ATP6AP1 polyclonal antibody

Swiss-Prot :Q15904

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :ATP6AP1 (ATPase, H+ transporting, lysosomal accessory protein 1), also known as 16A, CF2, Ac45, XAP3, ATP6S1, VATPS1 (vacuolar ATP synthase S1 accessory protein) or ATP6IP1, is a type I transmembrane, V-ATPase accessory protein that is predominantly expressed in endocrine and neuronal cells. ATP6AP1 is responsible for targeting the V-ATPase enzyme to specialized complex vacuolar systems. Via its cytoplasmic tail, ATP6AP1 interacts with subunits of the V0 domain. The disruption of this interaction in osteoclasts results in impaired bone resorption, suggesting an important role for ATP6AP1 in proper osteoclastic bone resorption.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ATP6AP1 polyclonal antibody detects endogenous levels of ATP6AP1 protein.

BiowMW :~ 52 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :V-type proton ATPase subunit S1; V-ATPase subunit S1; Protein XAP-3; V-ATPase Ac45 subunit; V-ATPase S1 accessory protein; Vacuolar proton pump subunit S1; ATP6AP1; ATP6IP1; ATP6S1; VATPS1; XAP3

Immunogen :Recombinant full length Human ATP6AP1.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of ATP6AP1 polyclonal antibody

Chronic exposure to microcystin-LR affected mitochondrial DNA maintenance and caused pathological changes of lung tissue in mice

JournalEnvironmental Pollution

ApplicationWB

IF6.792

SpeciesMouse

PMID26706032