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Cathepsin H polyclonal antibody

货号: BS61768
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS61768
Product Name :Cathepsin H polyclonal antibody
Swiss-Prot :P09668
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB
Application_all :WB: 1:500~1:1000
Background :Cathepsin H (also designated N-benzoylarginine-β-naphthylamide hydrolase, aleurain, cathepsin B3 or cathepsin BA) is a lysosomal cysteine proteinase that mediates degradation of lysosomal proteins. Cathepsin H is a disulfidelinked heavy and light chain dimer produced from a single precursor protein. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Elevated levels of cathepsin H correlates with malignant progression of prostate tumors. Two transcript variants encoding different isoforms have been found for this gene. Full-length and truncated cathepsin H [12 amino acid deletion in the signal peptide region (CTSH∆10-21)] are expressed in prostate tissues, LNCaP, PC-3 and DU-145 prostate cancer cell lines. Cathepsin H mediates maturation of the biologically active surfactant protein-B (SP-B) peptide.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Cathepsin H polyclonal antibody detects endogenous levels of Cathepsin H protein.
BiowMW :~ 37 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Pro-cathepsin H; Cathepsin H mini chain; Cathepsin H; Cathepsin H heavy chain; Cathepsin H light chain; CTSH; CPSB
Immunogen :Synthetic peptide, corresponding to amino acids 100-150 of Human Cathepsin H.
Conjugate :Unconjugated
Modification :Unmodification
Western blot (WB) analysis of Cathepsin H polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:AML-12 whole cell lysate(40ug) Lane4:PC3 whole cell lysate(10ug) Lane5:HepG2 whole cell lysate(10ug) Lane6:A549 whole cell lysate(10ug) Lane7:MCF-7 whole cell lysate(10ug)

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com