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CD6 polyclonal antibody

货号: BS61731

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61731

Product Name :CD6 polyclonal antibody

Swiss-Prot :P30203

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :CD6 is a type I transmembrane glycoprotein that is present on mature thymocytes, peripheral T cells and a subset of B cells. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T-cell activation and the size difference between the CD6 forms is due in part to differences in phosphorylation state. CD6 protein contains a 24-amino acid signal sequence, 3 extracellular “scavenger receptor cysteine-rich” (SRCR) domains, a membrane-spanning domain, and a 44-amino acid cytoplasmic domain. CD6 shows significant homology to CD5. CD6, which is also found in brain and B cell chronic lymphocytic leukemias, plays an important role in interactions of thymocytes with thymic epithelial cells. CD6 molecules can physically associate with the TCR/ CD3 complex.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD6 polyclonal antibody detects endogenous levels of CD6 protein.

BiowMW :~ 71 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :T-cell differentiation antigen CD6; T12; TP120; CD6; Soluble CD6; CD6

Immunogen :Synthetic peptide, corresponding to amino acids 250-300 of Human CD6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD6 polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate(40ug) Lane2:MCF-7 whole cell lysate(40ug) Lane3:H9C2 whole cell lysate(40ug) Lane4:AML-12 whole cell lysate(40ug)