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ARF4 (E106) polyclonal antibody（KU）

货号: BS3065

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS3065

Product Name :ARF4 (E106) polyclonal antibody（KU）

Swiss-Prot :P18085

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells. ARF-dependent regulatory mechanisms include the coordination of spectrin interactions with Golgi membranes and the association of actin to the Golgi via rho family-dependent G-protein localization (Rac, CDC42) and WASP/Arp2/3 complexes. Additionally, ARFs play a central role in maintenance of organelle integrity, assembly of coat proteins, and activation of phospholipase D. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6); members of each class share a common gene organization. The human ARF1 gene maps to chromosome 1q42, contains 5 exons and 4 introns, and encodes a 181 amino acid protein.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ARF4 (E106) polyclonal antibody detects endogenous levels of ARF4 protein.

BiowMW :~ 21 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ADP ribosylation factor 2; ADP ribosylation factor 4; ARF2;

Immunogen :Synthetic peptide, corresponding to amino acids 80-130 of Human ARF4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ARF4 (E106) pAb at 1:500 dilution Lane1:HepG2 whole cell lysate(40ug) Lane2:K562 whole cell lysate(40ug) Lane3:L02 whole cell lysate(40ug) Lane4:3T3-L1 whole cell lysate(40ug)