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BRCA2 (N60) polyclonal antibody

货号: BS2864

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2864

Product Name :BRCA2 (N60) polyclonal antibody

Swiss-Prot :P51587

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC

Application_all :IHC: 1:50~1:200

Background :BRCA 2 is localized to chromosome 13q12 - q13. Loss of heterozygosity of 13q is observed in 25% of sporadic breast tumors, which indicates that BRCA 2 might be a tumor suppressor gene. BRCA 2 confers only a low ovarian cancer risk. Reportedly, in MCF-10F (normal breast epithelial cell line) and MCF-7 (breast cancer cell line) cells the expression of BRCA 2 RNA lowers in G0 and early G1 phases then gets up-regulated at the G1 / S phase junction.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :BRCA2 (N60) polyclonal antibody detects endogenous levels of BRCA2 protein.

BiowMW :~ 384 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Fanconi anemia group D1 protein; Breast cancer type 2 susceptibility protein; BRCA2; FACD; FANCD1

Immunogen :Synthetic peptide, corresponding to amino acids 60-100 of Human BRCA2.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of BRCA2 (N60) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）