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ENX-2 (E192) polyclonal antibody（KU）

货号: BS2114

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2114

Product Name :ENX-2 (E192) polyclonal antibody（KU）

Swiss-Prot :Q92800

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG) proteins, which activate homeobox gene expression during embryonic development. ENX-1, a mammalian homolog of the Drosophila gene enhancer of zeste, is a PcG protein that is ubiquitously expressed during early embryogenesis and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development. In the adult, ENX-1 is restricted to specific sites, including spleen, testis and placenta. ENX-2 is another mammalian homolog of the Drosophila gene enhancer of zeste and contains one SET domain. The gene for human ENX-2 maps to chromosome 17q21. ENX-2 expression is ubiquitous in adult and fetal tissue, where it may aid in maintaining heterochromatin stability.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ENX-2 (E192) polyclonal antibody detects endogenous levels of ENX-2 protein.

BiowMW :~ 85 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Epigenetic Writers and Erasers of Histone H3,

Alternative Name :Histone-lysine N-methyltransferase EZH1; ENX2; Enhancer of zeste homolog 1; EZH1; KIAA0388

Immunogen :Synthetic peptide, corresponding to amino acids 162-208 of Human ENX-2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ENX-2 (E192) polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate(40ug) Lane2:A2780 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug) Lane5:HepG2 whole cell lysate(40ug) Lane6:H9C2 whole cell lysate(40ug) Lane7:3T3-L1 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of ENX-2 (E192) pAb in paraffin-embedded human brain tissue.