产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Sox2 monoclonal antibody

货号: MB0064

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB0064

Product Name :Sox2 monoclonal antibody

Swiss-Prot :P48431

Host :Mouse

Reactivity :Human,Mouse

Applications :WB ICC FC

Application_all :WB: 1:1000 ICC: 1:50~200 FC: 1:50~100

Background :SOX 2 is also known as SRY related HMG BOX gene 2. All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX 2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of Sox2 and does not cross-react with related proteins

BiowMW :Predicted band size:35KDa Observed band size:35KDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Neuronal and Glial Cell Marker Atlas,ESC Pluripotency and Differentiation Signaling Pathway,

Alternative Name :Transcription factor SOX-2

Immunogen :Recombinant full length Human Sox2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Sox2 antibody in F9 cell lysates using Sox2 antibody (1:1000 diluted) .

Flow Cytometry analysis of F9 cells stained with Sox2 (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.

Immunocytochemistry of COS7 cells using anti-Sox2 antibody diluted 1:150.

Cigarette Smoke-Induced Gastric Cancer Cell Exosomes Affected the Fate of Surrounding Normal Cells via the Circ0000670/Wnt/β-Catenin Axis

JournalToxics

ApplicationWB

IF4.472

SpeciesHuman

PMID37235279