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PTPα (I792) polyclonal antibody（KU）

货号: BS9115

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS9115

Product Name :PTPα (I792) polyclonal antibody（KU）

Swiss-Prot :P18433

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Protein tyrosine phosphatases, or PTPs, are type I transmembrane proteins, membrane associated proteins or proteins localized in nuclei. Examples of transmembrane PTPs are LAR, PTPα, PTPβ, PTPγ, PTPδ, PTPε, PTPζ, PTPκ, PTPμ and PTPσ. Transmembrane PTPσ play diverse roles during development and in adult tissues. Immunodepletion studies have suggested LAR to be a regulator of Insulin receptor phosphorylation. PTPα activity is increased twofold in response to phorbol ester stimulation, resulting in serine phosphorylation either directly or indirectly by members of the PKC family.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PTPα (I792) polyclonal antibody detects endogenous levels of PTPα protein.

BiowMW :~ 145 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Receptor-type tyrosine-protein phosphatase alpha; Protein-tyrosine phosphatase alpha; R-PTP-alpha; PTPRA; PTPA; PTPRL2; PTP-α

Immunogen :Synthetic peptide, corresponding to amino acids 760-810 of Human PTPα.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of PTPα (I792) pAb at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:CT26 whole cell lysate(40ug) Lane3:The Heart tissue lysate of Rat(40ug) Lane4:Panc1 whole cell lysate(20ug) Lane5:Hela whole cell lysate(20ug)