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PTN polyclonal antibody

货号: BS7504

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7504

Product Name :PTN polyclonal antibody

Swiss-Prot :P21246

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background :Pleiotrophin?(PTN) also known as?heparin-binding brain mitogen?(HBBM) or?heparin-binding growth factor 8?(HBGF-8) or?neurite growth-promoting factor 1?(NEGF1) or?heparin affinity regulatory peptide?(HARP) or?heparin binding growth associated molecule?(HB-GAM) is a?protein?that in humans is encoded by the?PTNgene.?Pleiotrophin is an 18-kDa?growth factor?that has a high affinity for?heparin. It is structurally related to?midkine?and?retinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PTN polyclonal antibody detects endogenous levels of PTN protein.

BiowMW :~19 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HARP; HB-GAM; HBBM; HBGAM; HBGF-8; HBGF8; HBNF; HBNF-1; HBNF1; heparin affin regulatory protein; Heparin binding growth associated molecule; Heparin Binding Growth Factor 8; Heparin binding neurite outgrowth promoting factor 1; Heparin-binding brain mitogen; heparin-binding growth associated molecule; Heparin-binding growth factor 8; Heparin-binding growth-associated molecule; Heparin-binding neurite outgrowth-promoting factor 1; NEGF1; Neurite Growth Promoting Factor 1; Neurite outgrowth-promoting factor, heparin-binding; OSF-1; OSF1; Osteoblast-specific factor 1; osteoblast-specific factor; pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1); Pleiotrophin; PTN; PTN_HUMAN;

Immunogen :Recombinant full length Human PTN.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PTN polyclonal antibody