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CDYL2 polyclonal antibody

货号: BS62337

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS62337

Product Name :CDYL2 polyclonal antibody

Swiss-Prot :Q8N8U2

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC ICC

Application_all :WB:1:500~1:1000 IHC:1:50~1:200 ICC:1:50~1:200

Background :CDY is a gene family expressed exclusively in the testis that localizes to a region of the Y chromosome frequently deleted in infertile males. CDY proteins contain two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and a C-terminal domain, which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY proteins act as histone acetyltransferases with strong preference for Histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein 2 (CDYL2) is a related nuclear protein that is ubiquitously expressed with moderate levels in most tissues. The gene encoding CDYL2 is located on chromosome 16.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CDYL2 polyclonal antibody detects endogenous levels of CDYL2 protein.

BiowMW :~ 57 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Chromodomain Y-like protein 2; CDY-like 2; CDYL2

Immunogen :Synthetic peptide, corresponding to Human CDYL2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CDYL2 polyclonal antibody at 1:500 dilution LaneA:CT26 whole cell lysate LaneB:PC12 whole cell lysate LaneC:Hela whole cell lysate LaneD:PC3 whole cell lysate