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MRPL10 polyclonal antibody（KU）

货号: BS61591

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS61591

Product Name :MRPL10 polyclonal antibody（KU）

Swiss-Prot :Q7Z7H8

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Mitochondria have their own translation machinery for production of 13 proteins that are required for oxidative phosphorylation. MRP-L10 (39S ribosomal protein L10, mitochondrial), also known as MRPL8, is a 261 amino acid protein that is a component of the large ribosomal subunit of the mitochondria. MRP-L10 is one of the 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome. MRP-L10 is deacteylated in a NAD+- dependent manner by SIRT3, which is an event that contributes to the regulation of mitochondrial protein synthesis. The gene encoding MRP-L10 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MRPL10 polyclonal antibody detects endogenous levels of MRPL10 protein.

BiowMW :~ 29 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :39S ribosomal protein L10, mitochondrial; L10mt; MRP-L10; 39S ribosomal protein L8, mitochondrial; L8mt; MRP-L8

Immunogen :Synthetic peptide, corresponding to amino acids 215-259 of Human MRPL10.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MRPL10 pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:DLD whole cell lysate(40ug) Lane3:U-87MG whole cell lysate(40ug) Lane4:HuT78 whole cell lysate(40ug)