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RDM1 polyclonal antibody

货号: BS61252

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61252

Product Name :RDM1 polyclonal antibody

Swiss-Prot :Q8NG50

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :RDM1 (RAD52motif-containing protein 1) is a 284 amino acid protein that is expressed in testis. RDM1 isinvolved in the cellular response to cisplatin, a drug commonly used in chemotherapy. Human RDM1 shares 71.1%and 51.2% amino acid identitywithmouse and chicken RDM1, respectively. RDM1 exists as 11 alternativelyspliced isoforms and only exon 3 iscommon to allvarants. Usage of two translationalstartsites, one in exon 1 and the other in intron 1, produces RDM1 isoformswith either long orshort N termini, and RDM1 isoforms have great diversityin their C termini as well. The RDM1 protein containstwomotifs: amotif found in Rad52, a protein that functions in DNA double-strand breaks and homologousrecombination, and an RNA recognitionmotif (RRM) that is not found in Rad52. The RDM1 gene contains seven coding exons, isconserved in chimpanzee,canine, bovine,mouse, rat, chicken and zebrafish, andmapsto human chromosome 17q12.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RDM1 polyclonal antibody detects endogenous levels of RDM1 protein.

BiowMW :~ 15 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RAD52 motif-containing protein 1; RAD52 homolog B; RDM1; RAD52B

Immunogen :A synthetic peptide corresponding to residues in Human RDM1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of RDM1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate