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MAG polyclonal antibody

货号: BS60807

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60807

Product Name :MAG polyclonal antibody

Swiss-Prot :P20916

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Myelin-associated glycoprotein (MAG) is a nervous system cell-surface adhesion protein that is involved in linking myelinating glial cells to neuronal axons. MAG contains a sialic acid binding site and five IgG-like domains, thus identifying MAG as a member of a subgroup of the immunoglobulin superfamily. Like myelin, MAG inhibits axonal outgrowth and contributes to the inhibitory properties of myelin. Growth inhibition by MAG has been shown to be blocked when cerebellar neurons are pre-incubated with the neurotrophins BDNF or GDNF. It is suggested that this neurotrophin priming elevates cAMP and activates PKA.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MAG polyclonal antibody detects endogenous levels of MAG protein.

BiowMW :~ 100 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Neuronal and Glial Cell Marker Atlas,

Alternative Name :Myelin-associated glycoprotein; Siglec-4a; MAG; GMA

Immunogen :A synthetic peptide corresponding to residues in Human MAG

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MAG polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate