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LTBP1 polyclonal antibody

货号: BS60783

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60783

Product Name :LTBP1 polyclonal antibody

Swiss-Prot :Q14766

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Latent transforming growth factor-beta 1 binding protein 1 (LTBP-1), a heavy glycoprotein, is part of the platelet-derived TGF-beta 1 complex. LTBP-1 serves as an anchor for latent TGF-beta in the extracellular matrix and is a component of microfibrillar structures. Cleavage of LTBP results in LTBP-1, which may sequester latent TGF-beta in the extracellular matrix and regulate its activation. LTBP-1 mRNA is enriched in ovarian carcinoma tissues and highly expressed in serous and mucinous adenocarcinomas.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LTBP1 polyclonal antibody detects endogenous levels of LTBP1 protein.

BiowMW :~ 187 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Latent-transforming growth factor beta-binding protein 1; LTBP-1; Transforming growth factor beta-1-binding protein 1; TGF-beta1-BP-1; LTBP1

Immunogen :A synthetic peptide corresponding to residues in Human LTBP1

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of LTBP1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate

Modulation of TGF‑β activity by latent TGF‑β‑binding protein 1 in human osteoarthritis fibroblast‑like synoviocytes

JournalMolecular Medicine Reports

ApplicationWB

IF2.1

SpeciesHuman

PMID29257223