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LPHN2 polyclonal antibody

货号: BS60779

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60779

Product Name :LPHN2 polyclonal antibody

Swiss-Prot :O95490

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LPHN2 polyclonal antibody detects endogenous levels of LPHN2 protein.

BiowMW :~ 220 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Latrophilin-2; Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; Latrophilin homolog 1; Lectomedin-1; LPHN2; KIAA0786; LEC1; LPHH1

Immunogen :A synthetic peptide corresponding to residues in Human LPHN2

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of LPHN2 pAb at 1:500 dilution Lane1:U-87MG whole cell lysate(40ug) Lane2:H1792 whole cell lysate(40ug) Lane3:HepG2 whole cell lysate(40ug)