产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

RBL1 polyclonal antibody

货号: BS60760

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60760

Product Name :RBL1 polyclonal antibody

Swiss-Prot :P28749

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The human retinoblastoma gene product plays an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. pRb and the structurally related p107 form complexes with E2F, a transcription factor originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Moreover, pRB and p107 share a high degree of structural homology in the adenovirus E1A binding domain (i.e. “pocket region”) that is believed to play a primary role in the function of these proteins. A protein designated p130 shows a high degree of identity with pRb and p107 and also possesses a pocket region.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RBL1 polyclonal antibody detects endogenous levels of RBL1 protein.

BiowMW :~ 121 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Retinoblastoma-like protein 1; 107 kDa retinoblastoma-associated protein; p107; pRb1; RBL1

Immunogen :A synthetic peptide corresponding to residues in Human RBL1

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of RBL1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate

A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells

JournalFebs Letters

ApplicationWB

IF2.675

SpeciesHuman

PMID20547158