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IL17A polyclonal antibody

货号: BS60297

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60297

Product Name :IL17A polyclonal antibody

Swiss-Prot :Q16552

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length, that is highly expressed in spleen and kidney.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL17A polyclonal antibody detects endogenous levels of IL17A protein.

BiowMW :~ 17, 30 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interleukin-17A; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8; CTLA8; IL17

Immunogen :A synthetic peptide corresponding to residues in Human IL17A.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IL17A polyclonal antibody at 1:500 dilution Lane1:THP-1 cell lysate Lane2:Raw264.7 cell lysate Lane3:H9C2 cell lysate

Interleukin-17A promotes tongue squamous cell carcinoma metastasis through activating miR-23b/versican pathway

JournalOncotarget

ApplicationIHC

IF0

SpeciesHuman

PMID28035060