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UBE4A polyclonal antibody

货号: BS5971

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS5971

Product Name :UBE4A polyclonal antibody

Swiss-Prot :Q14139

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :UBE4A (ubiquitin conjugation factor E4 A), also known as E4, UFD2 or UBOX2, is a 1,066 amino acid protein that functions in the multiubiquitin pathway of protein degradation. Expressed in cortical neurons and in tubular kidney cells, UBE4A is the human homolog of the Sacch-aromyces cerevisiae UFD2 protein and functions with the UBE (ubiquitin enzymes) proteins to catalyze ubiquitin chain assembly. UBE4A may be in-volved in cell growth and differentiation and can act as an autoantigen in scleroderma, a disease characterized by excessive deposits of collagen in the skin or other organs. Two isoforms of UBE4A exist due to alternative splicing events.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :UBE4A polyclonal antibody detects endogenous levels of UBE4A protein.

BiowMW :~ 125 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Ubiquitin Proteasome,

Alternative Name :Ubiquitin conjugation factor E4 A; KIAA0126

Immunogen :Synthetic peptide, corresponding to amino acids 183-228 of Human UBE4A.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of UBE4A polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate

免疫沉淀（IP）

免疫组织化学（IHC）