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ADAM17 Rabbit monoclonal antibody（KU）

货号: BS40435

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS40435

Product Name :ADAM17 Rabbit monoclonal antibody（KU）

Swiss-Prot :P78536

Host :Rabbit

Reactivity :Human Mouse Rat

Applications :WB ICC/IF IP FC

Application_all :WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:100

Background :TACE is responsible for the shedding of EGFR ligands such as amphiregulin and TNF-α. Some tumors have hyperactivated EGFR due to upregulated TNF-α production and upregulated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand-independent manner and has been shown to play a role in the development of the Drosophila nervous system.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :Affinity-chromatography

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ADAM17 Antibody detects endogenous levels of total ADAM17

BiowMW :100kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD156b; ADAM17; CSVP; TACE;

Immunogen :A synthesized peptide derived from human ADAM17

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of ADAM17 expression in Hela cell lysate.

ICC staining ADAM17 in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.