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ERR alpha Rabbit monoclonal antibody（KU）

货号: BS40192

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS40192

Product Name :ERR alpha Rabbit monoclonal antibody（KU）

Swiss-Prot :P11474

Host :Rabbit

Reactivity :Human Mouse Rat

Applications :WB IP FC

Application_all :WB 1:1000~1:2000 IP 1:50 FC 1:20

Background :Estrogen-related receptor alpha (ERRα/NR3B1) is an orphan nuclear receptor that controls transcription of genes involved in fatty acid oxidation, glucose metabolism, and mitochondrial biogenesis. The receptor protein contains a non-conserved amino terminal domain (NTD), a central zinc finger DNA binding domain, and a ligand-binding domain. The carboxy-terminal AF2 helix motif of ERRα contains binding sites for nuclear receptor coactivators PGC-1α and PGC-1β. Research studies demonstrate that ERRα transcriptional activity is regulated through phosphorylation and sumoylation within the NTD.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :Affinity-chromatography

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ERR alpha Antibody detects endogenous levels of ERR alpha

BiowMW :50kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ESRRA; ERRa; ERR1; HERR1; NR3B1; Steroid hormone receptor ERR1; ERR-alpha; ERRalpha; ESRL1; Estrogen receptor-like 1; Estrogen-related receptor alpha;

Immunogen :A synthesized peptide derived from human ERR alpha

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of ERR alpha expression in HeLa cell lysate.