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CCN2 polyclonal antibody（KU）

货号: BS3979

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3979

Product Name :CCN2 polyclonal antibody（KU）

Swiss-Prot :P29279

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB 1:1000~1:2000

Background :Connective tissue growth factor (CTGF, CCN2) belongs to the CCN (CYR61, CTGF, NOV) family of secreted extracellular matrix (ECM) proteins. Members of this family contain four conserved cysteine-rich domains, and interact in the ECM with a diverse array of cell surface receptors, including integrins and heparin-sulfate proteoglycans. These interactions regulate a multitude of cellular and tissue functions, including adhesion, proliferation, migration, differentiation, senescence, angiogenesis, inflammation, and wound repair. The CTGF gene is a transcriptional target of both YAP/TAZ and TGFβ-SMAD signaling pathways, and aberrant regulation of CTGF expression is strongly associated with pathological conditions, notably cancer and fibrosis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CCN2 polyclonal antibody detects endogenous levels of CCN2 protein.

BiowMW :~ 35 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8; CCN2; CTGF; HCS24; IGFBP8

Immunogen :Recombinant protein of human CCN2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CCN2 polyclonal antibody at 1:1000 dilution Lane1:HepG2 whole cell lysate(30ug) Lane2:A549 whole cell lysate(30ug)