产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

CEP290 (F812) polyclonal antibody（KU）

货号: BS3831

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3831

Product Name :CEP290 (F812) polyclonal antibody（KU）

Swiss-Prot :O15078

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes. CEP290 is ubiquitously expressed; strongly in placenta and weakly in brain. There are two named isoforms. Defects in CEP290 are a cause of Joubert syndrome type 5 (JBTS5), Senior-Loken syndrome type 6 (SLSN6), Leber congenital amaurosis type 10 (LCA10) and Meckel syndrome type 4 (MKS4). Antibodies against CEP290 are present in sera from patients with cutaneous T cell lymphomas, but not in the healthy control population.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CEP290 (F812) polyclonal antibody detects endogenous levels of CEP290 protein.

BiowMW :~ 290 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Centrosomal protein of 290 kDa; Cep290; Bardet-Biedl syndrome 14 protein; Cancer/testis antigen 87; CT87; Nephrocystin-6; Tumor antigen se2-2; CEP290; BBS14; KIAA0373; NPHP6

Immunogen :Synthetic peptide, corresponding to amino acids 781-830 of Human CEP290.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CEP290 (F812) polyclonal antibody at 1:500 dilution Lane1:HCT116 whole cell lysate(40ug) Lane2:SGC7901 whole cell lysate(40ug) Lane3:COS-7 whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug) Lane5:CT26 whole cell lysate(40ug) Lane6:AML-12 whole cell lysate(40ug) Lane7:PC12 whole cell lysate(40ug)