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CPM (L113) polyclonal antibody（KU）

货号: BS3827

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3827

Product Name :CPM (L113) polyclonal antibody（KU）

Swiss-Prot :P14384

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Carboxypeptidase M (CPM) is a 443 amino acid protein belonging to the metallo-carboxypeptidase (metallo-CP) family. Localized to the cell membrane, CPM contains hydrophobic regions in the N and C- termini and has six potential asparagine-linked glycosylation sites. Functionally, CPM specifically removes C-terminal basic amino acids (arginine or lysine) from proteins and polypeptides and is believed to play a role in monocyte to macrophage differentiation. CPM is also thought to play an important role in the control of peptide hormone and growth factor activity at the cell surface, as well as in the membrane-localized degradation of extracellular proteins. Three isoforms of this protein exist as a result of alternative splicing events.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CPM (L113) polyclonal antibody detects endogenous levels of CPM protein.

BiowMW :~ 51 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Carboxypeptidase M; CBPM; CPM; Renal carboxypeptidase; Urinary carboxypeptidase B

Immunogen :Synthetic peptide, corresponding to amino acids 80-130 of Human CPM.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CPM (L113) pAb at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:The Uterus tissue lysate of Mouse(40ug) Lane3:The Uterus tissue lysate of Rat(40ug)