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NCAM-L1 (R1177) polyclonal antibody

货号: BS3723

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS3723

Product Name :NCAM-L1 (R1177) polyclonal antibody

Swiss-Prot :P32004

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NCAM-L1 (R1177) polyclonal antibody detects endogenous levels of NCAM-L1 protein.

BiowMW :~ 140 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MIC 5; antigen identified by monoclonal antibody R1; MASA; CD 171; MIC5; N CAML1; SPG1; N CAM L1; HSAS; CD171; CD171 antigen; SPG 1; L1 cell adhesion molecule; HSAS1; HGNC:7086; NEURAL CELL ADHESION MOLECULE L1 PRECURSOR; S10; CAML1

Immunogen :Synthetic peptide, corresponding to amino acids 1150-1200 of Human NCAM-L1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of NCAM-L1 (R1177) polyclonal antibody in extracts from Raw264.7 cells treated with LPS.

Immunohistochemistry (IHC) analyzes of NCAM-L1 (R1177) pAb in paraffin-embedded human colon carcinoma tissue at 1:50.showing cell membrane staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.