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IL-1β (F162) polyclonal antibody

货号: BS3506

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3506

Product Name :IL-1β (F162) polyclonal antibody

Swiss-Prot :P01584

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:100~1:200

Background :Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL-1β (F162) polyclonal antibody detects endogenous levels of IL-1β protein.

BiowMW :~ 43, 35, 17 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Immune Cell Signaling,Inflammasonme Signaling,Necrotic Cell Death,

Alternative Name :Interleukin-1 beta; IL-1 beta; Catabolin; IL1B; IL1F2; IL-1β; IL1β

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-1 beta.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of IL-1β expression in Raw264.7 (A), mouse spleen (B), rat spleen (C), rat thymus (D), mouse thymus (E), Jurkat (F), THP1 (G) whole cell lysates.

Immunohistochemical analysis of IL-1β staining in human lung cancer formalin fixed paraffin embedded tissue section.

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