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CCK-BR (L54) polyclonal antibody（KU）

货号: BS3159

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3159

Product Name :CCK-BR (L54) polyclonal antibody（KU）

Swiss-Prot :P32239

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :CCKBR is a G protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR is most abundant in brain and stomach but it can also be found in colon, pancreas, thyroid, and various cancers.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CCK-BR (L54) polyclonal antibody detects endogenous levels of CCK-BR protein.

BiowMW :~ 48 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R; CCKBR; CCKRB

Immunogen :Synthetic peptide, corresponding to amino acids 30-80 of Human CCK-BR.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CCK-BR (L54) pAb at 1:500 dilution Lane1:Panc1 whole cell lysate(40ug) Lane2:SGC7901 whole cell lysate(40ug) Lane3:The Brain tissue lysate of Mouse(20ug) Lane4:The Brain tissue lysate of Rat(40ug)

Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells

JournalBmc Cancer

ApplicationWB

IF4.43

SpeciesHuman

PMID28109268