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SIP1 (E101) polyclonal antibody

货号: BS3009

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3009

Product Name :SIP1 (E101) polyclonal antibody

Swiss-Prot :O60315

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :SIP1, also known as SMADIP1 and ZFHX1B, can be induced by TGFβ treatment. SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest. The human SIP1 gene maps to chromosome 2q22. Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR). Patients with SIP1 mutations show mental retardation, delayed motor development, epilepsy, microcephaly, distinct facial features and/or congenital heart disease—all symptoms of HSCR.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SIP1 (E101)pAb detects endogenous levels of SIP1 protein.

BiowMW :~ 157 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Zinc finger E-box-binding homeobox 2; Smad-interacting protein 1; SMADIP1; Zinc finger homeobox protein 1b; ZEB2; KIAA0569; SIP1; ZFHX1B; ZFX1B; HRIHFB2411

Immunogen :Synthetic peptide, corresponding to amino acids 71-120 of Human SIP1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SIP1 (E101) polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:HEK293T whole cell lysate Lane3:NIH-3T3 whole cell lysate

Immunohistochemistry (IHC) analyzes of SIP1 (E101) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.

ZEB2 Mediates Multiple Pathways Regulating Cell Proliferation, Migration, Invasion, and Apoptosis in Glioma

JournalPLoS One

ApplicationIHC

IF3.24

SpeciesHuman

PMID22761708