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Sam 68 (Y145) polyclonal antibody（KU）

货号: BS2952

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2952

Product Name :Sam 68 (Y145) polyclonal antibody（KU）

Swiss-Prot :Q07666

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :SAM68 is recruited and tyrosine phosphorylated by several receptor systems, and once it is phosphorylated, it functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins.It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. It also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Sam 68 (Y145) polyclonal antibody detects endogenous levels of Sam 68 protein.

BiowMW :~ 48 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KH domain-containing; RNA-binding; signal transduction-associated protein 1; GAP-associated tyrosine phosphoprotein p62; Src-associated in mitosis 68 kDa protein; Sam68; p21 Ras GTPase-activating protein-associated p62; p68; KHDRBS1; SAM68

Immunogen :Synthetic peptide, corresponding to amino acids 120-170 of Human Sam 68.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Sam 68 (Y145) pAb at 1:1000 dilution Lane1:HCC827 whole cell lysate(40ug) Lane2:Hela whole cell lysate(40ug) Lane3:H9C2 whole cell lysate(40ug) Lane4:3T3-L1 whole cell lysate(40ug)