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Synphilin-1 (R846) polyclonal antibody（KU）

货号: BS2939

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2939

Product Name :Synphilin-1 (R846) polyclonal antibody（KU）

Swiss-Prot :Q9Y6H5

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Synphilin-1 (α-synuclein interacting protein, SNCAIP) is a 919 amino acid protein that associates with α synuclein and promotes the formation of cytosolic inclusions in neuronal cells. The synuclein family members, including α-synuclein and β-synuclein, are predominantly expressed in the brain, where they influence synaptic regulation and neuronal plasticity. Synphilin-1 contains modular protein domains, such as ankyrin-like repeats and a coiled-coil domain.While both α-synuclein and synphilin-1 are coexpressed in Lewy bodies of patients with Parkinson’s disease, only mutations in the gene for α-synuclein have been determined to confer pathogenicity.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Synphilin-1 (R846) polyclonal antibody detects endogenous levels of Synphilin-1 protein.

BiowMW :~ 100 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Synphilin-1; Sph1; Alpha-synuclein-interacting protein; SNCAIP

Immunogen :Synthetic peptide, corresponding to amino acids 815-867 of Human Synphilin-1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Synphilin-1 (R846) pAb at 1:500 dilution Lane1:3T3-L1 whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug) Lane4:HEK293T whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Synphilin-1 (R846) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.