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Ki-67 (V3242) polyclonal antibody

货号: BS1454

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1454

Product Name :Ki-67 (V3242) polyclonal antibody

Swiss-Prot :P46013

Host :Rabbit

Reactivity :Human

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Ki-67 is a nuclear protein that is expressed in proliferating cells and may be required for maintaining cell proliferation. Ki-67 has been used as a marker for cell proliferation of solid tumors and some hematological malignancies. A correlation has been demonstrated between Ki-67 index and the histopathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Ki-67 (V3242) polyclonal antibody detects endogenous levels of Ki-67 protein.

BiowMW :~ 359 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Neuronal and Glial Cell Marker Atlas,

Alternative Name :Antigen KI-67; MKI67; Ki67; Ki 67

Immunogen :Synthetic peptide, corresponding to amino acids C-terminus of Human Ki-67.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Ki-67 (V3242) pAb at 1:500 dilution Lane1:HCT116 whole cell lysate(40ug) Lane2:U-87MG whole cell lysate(40ug) Lane3:HepG2 whole cell lysate(40ug) Lane4:L02 whole cell lysate(40ug) Lane5:SK-OVCAR3 whole cell lysate(40ug) Lane6:DLD whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Ki-67 (V3242) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer

JournalInternational Journal Of Biochemistry & Cell Biology

ApplicationWB

IF3.673

SpeciesHuman,Mouse

PMID
ClC‐3 Promotes Osteogenic Differentiation in MC3T3‐E1 Cell After Dynamic Compression

JournalJournal Of Cellular Biochemistry

ApplicationWB

IF4.237

SpeciesMouse

PMID27922190
LncRNA-AF113014 promotes the expression of Egr2 by interaction with miR-20a to inhibit proliferation of hepatocellular carcinoma cells

JournalPLoS One

ApplicationIHC

IF2.776

SpeciesHuman

PMID28542387
Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer

JournalJournal Of Experimental & Clinical Cancer Research

ApplicationIHC

IF7.068

SpeciesMouse

PMID30975171
Primed atypical ductal hyperplasia-associated fibroblasts promote cell growth and polarity changes of transformed epithelium-like breast cancer MCF-7 cells via miR-200b/c-IKKβ signaling

JournalCell Death & Disease

ApplicationIF

IF5.959

SpeciesHuman

PMID29374150