产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

TGFβ1 (Y369) polyclonal antibody（KU）

货号: BS1361

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1361

Product Name :TGFβ1 (Y369) polyclonal antibody（KU）

Swiss-Prot :P01137

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:5000~1:10000

Background :Transforming growth factor betas (TGFβs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFα. It is now realized that TGFβs mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGFβ1, TGFβ2 and TGFβ3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TGF β1 (Y369) polyclonal antibody detects endogenous levels of TGF β1 protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Tumor Angiogenesis,Contribution of Soluble Factors to EMT,TGFβ Smad signaling,

Alternative Name :Transforming growth factor beta-1; TGF-beta-1; Latency-associated peptide; LAP; TGFB1; TGFB; TGF β1

Immunogen :Synthetic peptide, corresponding to Human TGFβ1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TGFβ1 (Y369) pAb at 1:5000 dilution Lane1:C6 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug) Lane4:Hela whole cell lysate(40ug)

Anti-Fibrosis Effect of Relaxin and Spironolactone Combined on Isoprenaline-Induced Myocardial Fibrosis in Rats via Inhibition of Endothelial–Mesenchymal Transition

JournalCellular Physiology And Biochemistry

ApplicationWB

IF0

SpeciesHuman

PMID28245473
Tangshen Formula Improves Diabetes-Associated Myocardial Fibrosis by Inhibiting TGF-β/Smads and Wnt/β-Catenin Pathways.

JournalFrontiers in Medicine

ApplicationWB

IF5.091

SpeciesMouse

PMID34938743
HSPA12B promotes functional recovery after ischaemic stroke through an eNOS‐dependent mechanism

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF4.486

SpeciesMouse

PMID29411514
Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF4.486

SpeciesHuman

PMID31328391
Application of multiparametric MR imaging to predict the diversification of renal function in miR29a-mediated diabetic nephropathy

JournalScientific Reports

ApplicationIHC

IF4.379

SpeciesMouse

PMID33479331