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TGFβ1 (Y369) polyclonal antibody（KU）

货号: BS1361

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1361

Product Name :TGFβ1 (Y369) polyclonal antibody（KU）

Swiss-Prot :P01137

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:5000~1:10000

Background :Transforming growth factor betas (TGFβs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFα. It is now realized that TGFβs mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGFβ1, TGFβ2 and TGFβ3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TGF β1 (Y369) polyclonal antibody detects endogenous levels of TGF β1 protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Tumor Angiogenesis,Contribution of Soluble Factors to EMT,TGFβ Smad signaling,

Alternative Name :Transforming growth factor beta-1; TGF-beta-1; Latency-associated peptide; LAP; TGFB1; TGFB; TGF β1

Immunogen :Synthetic peptide, corresponding to Human TGFβ1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TGFβ1 (Y369) pAb at 1:5000 dilution Lane1:C6 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug) Lane4:Hela whole cell lysate(40ug)

Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway – an in vitro and in clinic study

JournalBMC Complementary Medicine and Therapies

ApplicationIHC

IF2.838

SpeciesHuman

PMID36447209
Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease

JournalINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ApplicationWB,IHC

IF6.208

SpeciesHuman

PMID37108841
Exosomal hsa_circ_000200 as a potential biomarker and metastasis enhancer of gastric cancer via miR-4659a/b-3p/HBEGF axis

JournalCancer Cell International

ApplicationWB

IF5.8

SpeciesHuman

PMID37525152
Effect of sequential release of sirolimus and rosuvastatin using silk fibroin microneedle to prevent intimal hyperplasia

JournalBIOMEDICINE & PHARMACOTHERAPY

ApplicationWB

IF7.5

SpeciesRabbit

PMID37837879
Chlorogenic acid alleviate kidney fibrosis through regulating TLR4/NF-қB mediated oxidative stress and inflammation

JournalJOURNAL OF ETHNOPHARMACOLOGY

ApplicationWB

IF4.8

SpeciesMouse,Human

PMID39142620