产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

TGFβ1 (Y369) polyclonal antibody（KU）

货号: BS1361

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1361

Product Name :TGFβ1 (Y369) polyclonal antibody（KU）

Swiss-Prot :P01137

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:5000~1:10000

Background :Transforming growth factor betas (TGFβs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFα. It is now realized that TGFβs mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGFβ1, TGFβ2 and TGFβ3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TGF β1 (Y369) polyclonal antibody detects endogenous levels of TGF β1 protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Tumor Angiogenesis,Contribution of Soluble Factors to EMT,TGFβ Smad signaling,

Alternative Name :Transforming growth factor beta-1; TGF-beta-1; Latency-associated peptide; LAP; TGFB1; TGFB; TGF β1

Immunogen :Synthetic peptide, corresponding to Human TGFβ1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TGFβ1 (Y369) pAb at 1:5000 dilution Lane1:C6 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug) Lane4:Hela whole cell lysate(40ug)

Smad3 is the key to transforming growth factor-β1-induced osteoclast differentiation in giant cell tumor of bone

JournalMedical Oncology

ApplicationIHC

IF3.252

SpeciesHuman

PMID23690270
Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli

JournalEuropean Journal Of Pharmacology

ApplicationWB

IF3.17

SpeciesRat

PMID23376562
Pyridostigmine Ameliorates Cardiac Remodeling Induced by Myocardial Infarction via Inhibition of the Transforming Growth Factor-β1/TGF-β1–Activated Kinase Pathway

JournalJournal Of Cardiovascular Pharmacology

ApplicationWB

IF3.105

SpeciesRat

PMID24805145
Preliminary study on the effect of trauma-induced secondary cellular hypoxia in brain injury

JournalNeuroscience Letters

ApplicationIHC

IF3.046

SpeciesRat

PMID
TGFβ1 and HGF protein secretion by esophageal squamous epithelial cells and stromal fibroblasts in oesophageal carcinogenesis

JournalOncology Letters

ApplicationIHC

IF2.967

SpeciesHuamn

PMID24137336