产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

OPN (L285) polyclonal antibody

货号: BS1264

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1264

Product Name :OPN (L285) polyclonal antibody

Swiss-Prot :P10451

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Osteopontin (OPN), also designated bone sialoprotein 1, urinary stone protein, spp-1, Eta-1, nephropontin and uropontin, is an extracellular matrix cell adhesion phosphoglycoprotein. OPN is deposited into unmineralized matrix prior to calcification leading to localization at various tissue interfaces including cement lines, lamina limitans and between collagen fibrils of fully matured hard tissues. While OPN is a major product of osteoblasts, it is also synthesized by brain and kidney cells. OPN isolated from or secreted by various tissues ranges in molecular weight due to posttranslational modifications. OPN functions as a substrate for transglutaminase and is involved in cell adhesion, chemoattraction and immunomodulation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :OPN (L285) polyclonal antibody detects endogenous levels of OPN protein.

BiowMW :~ 35, 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BNSP; Bone sialoprotein 1; BSP I; BSPI; Early T lymphocyte activation 1; ETA 1; ETA1; Nephropontin; OPN; Osteopontin; OSTP; Secreted phosphoprotein 1; SPP 1; SPP-1; SPP1; Urinary stone protein; Uropontin;

Immunogen :Synthetic peptide, corresponding to amino acids 251-300 of Human OPN.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of OPN (L285) polyclonal antibody at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:AML-12 whole cell lysate(40ug) Lane3:L02 whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug)

Hydroxysafflor yellow A promotes osteogenesis and bone development via epigenetically regulating β-catenin and prevents ovariectomy-induced bone loss

JournalInternational Journal Of Biochemistry & Cell Biology

ApplicationIHC

IF5.085

SpeciesRat

PMID34216755
Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification

JournalExperimental And Molecular Medicine

ApplicationWB

IF4.743

SpeciesPig

PMID31292436
MiR155 modulates vascular calcification by regulating Akt‐FOXO3a signalling and apoptosis in vascular smooth muscle cells

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF4.486

SpeciesMouse

PMID33210462
Celastrol attenuates arterial and valvular calcification via inhibiting BMP2/Smad1/5 signalling

JournalJournal Of Cellular And Molecular Medicine

ApplicationIF,WB

IF4.486

SpeciesMouse,Pig,Human

PMID32954678
The role of Rho-GEF Trio in regulating tooth root development through the p38 MAPK pathway

JournalExperimental Cell Research

ApplicationWB

IF3.329

SpeciesHuman,Mouse

PMID30268758