产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

COL4A1 (G46) polyclonal antibody

货号: BS1072

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1072

Product Name :COL4A1 (G46) polyclonal antibody

Swiss-Prot :P02462

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial Collagens (Types I, II, III and V) and basement membrane Collagens (Type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :COL4A1 (G46) polyclonal antibody detects endogenous levels of COL4A1 protein.

BiowMW :~ 300 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Collagen alpha-1(IV) chain; Arresten; Collagen IV; Collagen-IV; CollagenIV; Collagen4; Collagen 4; Collagen-4;

Immunogen :Synthetic peptide, corresponding to amino acids 11-60 of Human COL4A1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of COL4A1 (G46) polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat liver tissue lysate

Immunohistochemistry (IHC) analyzes of COL4A1 (G46) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Hesperetin ameliorates diabetic nephropathy in rats by activating Nrf2/ARE/glyoxalase 1 pathway

JournalBiomedicine & Pharmacotherapy

ApplicationIHC

IF4.545

SpeciesRat

PMID30841430
Ginsenoside Rg1 ameliorates glomerular fibrosis during kidney aging by inhibiting NOX4 and NLRP3 inflammasome activation in SAMP8 mice

JournalInternational Immunopharmacology

ApplicationIHC

IF3.943

SpeciesMouse

PMID32114413
Ginsenoside Rg1 protects against aging-induced renal interstitial fibrosis due to inhibition of tubular epithelial cells endoplasmic reticulum stress in SAMP8 mice

JournalJournal of Functional Foods

ApplicationIHC

IF3.701

SpeciesMouse

PMID
The role of transcription factor Ap1 in the activation of the Nrf2/ARE pathway through TET1 in diabetic nephropathy

JournalCell Biology International

ApplicationWB

IF3.612

SpeciesRat,Human

PMID33760331
C-peptide prevents SMAD3 binding to alpha promoters to inhibit collagen type IV synthesis

JournalJournal Of Molecular Endocrinology

ApplicationIHC,WB

IF3.562

SpeciesRat

PMID29844093