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COL4A1 (G46) polyclonal antibody

货号: BS1072

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1072

Product Name :COL4A1 (G46) polyclonal antibody

Swiss-Prot :P02462

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial Collagens (Types I, II, III and V) and basement membrane Collagens (Type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :COL4A1 (G46) polyclonal antibody detects endogenous levels of COL4A1 protein.

BiowMW :~ 300 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Collagen alpha-1(IV) chain; Arresten; Collagen IV; Collagen-IV; CollagenIV; Collagen4; Collagen 4; Collagen-4;

Immunogen :Synthetic peptide, corresponding to amino acids 11-60 of Human COL4A1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of COL4A1 (G46) polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat liver tissue lysate

Immunohistochemistry (IHC) analyzes of COL4A1 (G46) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Ginsenoside Rg1 ameliorates aging‑induced liver fibrosis by inhibiting the NOX4/NLRP3 inflammasome in SAMP8 mice

JournalMolecular Medicine Reports

ApplicationIHC

IF2.952

SpeciesMouse

PMID34523690
Ginsenoside Rg1 attenuates LPS-induced chronic renal injury by inhibiting NOX4-NLRP3 signaling in mice

JournalBIOMEDICINE & PHARMACOTHERAPY

ApplicationWB,IHC

IF6.53

SpeciesMouse

PMID35421784
Ginsenoside Rg1 treatment alleviates renal fibrosis by inhibiting the NOX4–MAPK pathway in T2DM mice

JournalRENAL FAILURE

ApplicationIF,WB

IF3.222

SpeciesHuman

PMID37017270