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p38 (V318) polyclonal antibody（KU）

货号: AP0424

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :AP0424

Product Name :p38 (V318) polyclonal antibody（KU）

Swiss-Prot :Q16539

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IP IF IHC

Application_all :WB: 1:1000~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200 IP: 1:50~1:200

Background :MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38α, p38β and p38γ are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p38 (V318) polyclonal antibody detects endogenous levels of p38 protein.

BiowMW :~ 42 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; SAPK2a; MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A

Immunogen :Synthetic peptide, corresponding to Human p38.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of p38 (V318) polyclonal antibody at 1:1000 dillution Lane1:HEK293T whole cell lysate(36μg) Lane2:NIH-3T3 whole cell lysate(38.8μg) Lane3:HepG2 whole cell lysate(36.8μg)

Immunoprecipitation of U-87MG cell lysates using p38 (V318) pAb (Sepharose Bead Conjugate)#BD0048 (lane 3 and lane 4) and Nonspecific IgG Control (Sepharose Bead Conjugate)#BD0048 (lane 1 and lane 2) .Lane 5 is 30% input. The western blot was probed using p38 (V318) pAb #AP0424.

Immunofluorescence analysis of U-87MG cells using p38 (V318) antibody at dilution of 1:50.

Immunohistochemistry of paraffin-embedded Rat Brain using p38 (V318) antibody at dilution of 1:50.

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