Product Name :p38 (V318) polyclonal antibody（KU）
Reactivity :Human,Mouse,Rat
Applications :WB IP IF IHC
Application_all :WB: 1:1000~1:2000
IHC: 1:50~1:200
IF: 1:50~1:200
IP: 1:50~1:200
Background :MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38α, p38β and p38γ are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :p38 (V318) polyclonal antibody detects endogenous levels of p38 protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Tumor Angiogenesis,NF-kB Signaling,Phospholipase Signaling,Signaling Pathways Activating p38 MAP Kinase,T cell receptor signaling,TGFβ Smad signaling,Toll-like Receptor signaling,Translational Contral elF4 and p70 S6 Kinase,
Alternative Name :Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; SAPK2a; MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A
Immunogen :Synthetic peptide, corresponding to Human p38.
Modification :Unmodification
